Table 2. Analyses for predictive factors for PET-detected metastasis.

Clinicopathological parameters	RR	95% CI	P
Univariant analysis
Age >65 years	0.960	0.920–1.001	0.056
Male sex	0.510	0.110–2.360	0.389
Hepatitis B	0.436	0.153–1.248	0.122
Child-Pugh class A	0.226	0.075–0.675	0.008*
ICG >14%	0.760	0.139–4.153	0.751
Bilirubin >40 μmol/L	2.722	0.162–45.851	0.487
Albumin <39 g/L	0.634	0.038–10.586	0.751
Platelet <150×109/L	0.267	0.058–1.227	0.090
Size of largest tumor >6.5 cm	2.911	0.972–8.720	0.056
Multifocal disease	4.45	1.38–14.35	0.013*
Bilobar involvement	5.50	1.82–16.63	0.003*
AFP ≥400 ng/mL	5.61	1.93–16.35	0.002*
Invasion of major branch of portal or hepatic vein	2.262	0.722–7.089	0.161
Multivariant analysis
AFP ≥400 ng/mL	4.30	1.41–13.15	0.011*
Bilobar HCC	3.94	1.24–12.52	0.014*
Age >65 years	–	–	NS
Child-Pugh class A	–	–	NS
Largest tumor size >6.5 cm	–	–	NS
Multifocal disease	–	–	NS
Platelet <150×109/L	–	–	NS

*, statistically significant. PET, positron emission tomography; RR, relative risk; CI, confidence interval; ICG, indocyanine green retention rate at 15 minutes after injection; NS, not significant; HCC, hepatocellular carcinoma; AFP, alpha-fetoprotein.