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Lidocaine attenuates proliferation of ovarian cancer cells in vivo. The nude mice were injected with SKOV-3 cells and treated with lidocaine (1.5 mg/kg). The tumor tissues (A), tumor volume (B), and tumor weight (C) were shown. (D) The expression of miR-382-5p was analyzed by qPCR assays. (E) The protein expression of SLC7A11 was detected by Western blot analysis. The results were quantified using ImageJ software. N = 5, mean ± SD, **p < 0.01.
