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. 2021 Mar 16;8(11):2100143. doi: 10.1002/advs.202100143

Figure 1.

Figure 1

Schematic diagram of the experimental design and characterizations of sequential release system. A) Scheme of designed multiporous tunnels for sequential release of Dex and rhBMP‐2. A burst release of Dex aims to precisely modulate an appropriate inflammatory response in the early stage, and thus promotes the sustained‐release rhBMP‐2‐induced EO bone regeneration. SEM images of macroporous structure B) and microporous structure C). D) TEM image of mesoporous structure. E) Mesopore size distribution. F) Release curve of rhBMP‐2. G) Release curves of Dex.