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. 2023 Jan 13;6:102. Originally published 2021 May 10. [Version 2] doi: 10.12688/wellcomeopenres.16729.2

Table 1. Possible data sets for occupational analyses.

Data source Occupation data Confounders Outcome data Availability to
researchers?
Office of National Statistics (ONS) data
Numerator: ONS registered deaths
Denominator: Annual Population Survey
Current occupation Age, sex, residence,
deprivation, ethnicity
COVID-19 on death
certificate
Yes
National Health Service (NHS) data
NHS hospitalization data No Age, sex, residence,
deprivation, ethnicity
COVID-19 admission Yes
NHS workplace absence reports Current occupation Unknown COVID-19 as cause Yes
OpenSafely No Age, sex, residence,
deprivation, ethnicity,
comorbidities
Hospital death from
COVID-19
Yes
HSE data
Workplace sickness reports (RIDDOR) Current occupation No COVID-19 as cause Yes
Population cohorts
UK Biobank + many others Most are using Wellcome COVID-19 questionnaire;
includes employment, sector, travel to work
Multiple SARS-CoV-2 positive test Yes (UK
Biobank)
Population surveys
ONS Infection Survey Current occupation, working from home, transport Age, sex, ethnicity,
geographical identifiers
Series of SARS-CoV-2
tests
Yes, under
application
Understanding Society Employment, work conditions, travel to work - key
work sector, industry, 3-digit SOC code.
Age, sex, ethnicity,
geographical identifiers
SARS-CoV-2 test
Symptoms
Yes
Real-time Assessment of Community Transmission
(REACT)
Unknown Yes COVID-19 symptoms and
test results
Possible
Apps
ZOE (King’s College) Not currently Yes COVID-19 symptoms and
test results
Possible
Population testing
Pillar 1 No No SARS-CoV-2 test Possible
Pillar 2 No No SARS-CoV-2 test Possible
Test-Trace-Isolate (TTI) No No Close contacts Possible
HSE/PHE data
Publica Health England (PHE) outbreak
investigations 10
Current occupation and exposures Age, sex, residence,
deprivation, ethnicity
SARS-CoV-2 test Yes