Table 3.
HLA I antigenic epitopes predicted using Rankpep.
| Sl. No | Alleles | SARS-CoV1 | SARS-CoV2 | MERS-CoV |
|---|---|---|---|---|
| 1 | HLA_A0201 | 15–23 QLSLPVLQV 84–92 KVVELVAEM 103–111 TLGVLVPHV 169–177 ALRELTREL |
84–92 VMVELVAEL 15–23 QLSLPVLQV 106–114 VLVPHVGEI |
135–143 ELVTGKQNI 89–97 YLVERLIAC 62–70 MLLKKEPLL 75–83 RLAGHTRHL |
| 2 | HLA_A0204 | 78–86 STNHGHKVV |
78–86 TAPHGHVMV 45–53 HLKDGTCGL |
80–88 TRHLPGPRV 3–11 FVAGVTAQC |
| 3 | HLA_A0206 | 103–111 TLGVLVPHV 38–46 ALSEAREHL |
106–114 VLVPHVGEI 103–111 TLGVLVPHV |
- |
| 4 | HLA_A0301 | 121–129 VLLRKNGNK |
121–129 VLLRKNGNK |
57–66 EVVKAMLLKK |
| 5 | HLA_A11 | - | - | 58–66 VVKAMLLKK |
| 6 | HLA_A1101 | 76–84 ALSTNHGHK |
3–11 SLVPGFNEK |
- |
| 7 | HLA_A2402 | 96–104 QYGRSGITL |
153–161 PYEDFQENW 96–104 QYGRSGETL |
- |
| 8 | HLA_A31 | 116–124 IAYRNVLLR |
116–124 VAYRKVLLR |
154–162 HYTPFHYER |
| 9 | HLA_A6801 | 116–124 IAYRNVLLR 76–84 ALSTNHGHK |
- | - |
| 10 | HLA_B0702 | - | 114–122 IPVAYRKVL |
- |
| 11 | HLA_B2705 | - | 76–84 ARTAPHGHV |
74–82 IRLAGHTRH |
| 12 | HLA_B35 | - | - | 124–132 KPIGMFFPV |
| 13 | HLA_B3501 | 61–69 LPQLEQPYV |
61–69 LPQLEQPYV |
33–42 VPLCGSGNLV 99–108 NPFMVNQLAY |
| 14 | HLA_B51 | 61–69 LPQLEQPYV 108–116 VPHVGETPI |
61–69 LPQLEQPYV |
83–91 LPGPRVYLV 33–41 VPLCGSGNL |
| 15 | HLA_B5101 | 108–116 VPHVGETPI 18–26 LPVLQVRDV |
108–116 VPHVGEIPV 114–122 IPVAYRKVL 18–26 LPVLQVRDV |
- |
| 16 | HLA_B5102 | 61–69 LPQLEQPYV 18–26 LPVLQVRDV |
- | - |
| 17 | HLA_B5103 | 108–116 VPHVGETPI 18–26 LPVLQVRDV |
18–26 LPVLQVRDV |
- |
| 18 | HLA_B5401 | - | - | 83–91 LPGPRVYLV |
| 19 | HLA_X | 169–177 ALRELTREL |
- | 82–90 HLPGPRVYL 124–132 KPIGMFFPY 128–136 MFFPYDIEL |