REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Rabbit polyclonal Anti-Gapdh	Sigma	CAT# SAB2701826;
Rabbit polyclonal Anti-Sod2	GeneTex	CAT#GTX124294; RRID:AB_11174816
Rabbit polyclonal Anti-Sirt3	Sigma	CAT#AV32388; RRID:AB_1856904
Mouse monoclonal Anti-Mtco1	Abcam	CAT#ab14705; RRID:AB_2084810
Rabbit polyclonal Acetyl-Lysine antibody	Cell Signaling Technology	CAT#9441; RRID:AB_331805
Rabbit polyclonal Anti-Sod2 K132pro	This paper	N/A
Bacterial and virus strains
Aeromonas veronii Hm091	Pearl River Fisheries Research Institute	N/A
Chemicals, peptides, and recombinant proteins
4-Hydroxy-TEMPO	Sigma	CAT#176141
Protease inhibitor cocktail	Cell Signaling Technology	CAT#5871
AlarmaBlue cell viability reagent	Invitrogen	CAT#DAL1025
Sodium oleate	Sigma	CAT#O7501
Palmitic acid	Sigma	CAT#P5585
Sodium propionate	Sigma	CAT#P1880
DCFH-DA	Beyotime	CAT#S0033S
Propionyl coenzyme A sodium salt	zzstandard	CAT#ZL-21372
PMSF	Beyotime	CAT#ST506
Lipofectamine 3000 transfection reagent	Invitrogen	CAT#L3000008
Lipofectamine RNAiMAX transfection reagent	Invitrogen	CAT#13778
SYBR Green Supermix	TIANGEN	CAT#FP205
Critical commercial assays
ToxinSensor Chromogenic LAL Endotoxin Assay Kit	Genscript	CAT#L00350
Caspase-9 Activity Assay Kit	Beyotime	CAT#C1158
Fluorometric Intracellular Ros Kit	Sigma	CAT#MAK143
Lipid Peroxidation (MDA) Assay Kit	Sigma	CAT#MAK085
Protein Carbonyl Content Assay Kit	Sigma	CAT#MAK094
Total Antioxidant Capacity Assay Kit	Beyotime	CAT#S0116
CuZn/Mn-SOD Activity Kit	Beyotime	CAT#S0103
Annexin V-FITC Apoptosis Kit	Sigma	CAT#apoaf
QuikChange Site-Directed Mutagenesis Kit	Stratagene	CAT#200523
Deposited data
Microbiota sequencing data	This paper	BioProject: PRJNA714780
Experimental models: Cell lines
ZF4: zebrafish embryo	ATCC	CRL-2050
Experimental models: Organisms/strains
Zebrafish: Tübingen strain	China Zebrafish Resource Center	CZ3
Oligonucleotides
siRNA	This paper	Table S5
Primers	This paper	Table S6
Recombinant DNA
Plasmids: pCDHA3.1-flag-Sod2, pCDHA3.1-flag-Sod2132K/Q and pCDHA3.1-flag-Sod2 132K/R	This paper	N/A
Plasmid: pCDHA3.1-his-flag-Sod2	This paper	N/A
Software and algorithms
Guava easyCyte Flow Cytometer software	Merck Millipore, Stafford, VA, USA	N/A
GraphPad Prism 5	GraphPad Software Inc., San Diego, CA, USA	N/A