Table 3.

Explanatory variables associated with progression free survival. Multivariable analysis with cox regression taking the PFS1 as the dependant variable. Variables entered Variables entered in the final model: sex, calcemia, renal disease, anemia, plasmocytes

Model 2: Cox regression taking the overall survival (in months) as the dependent variable.
Variable	Unadjusted HR	p; 95% CI	Adjusted HR	p; 95% CI
Age	1.02	0.410; 0.98-1.06
Gender (females vs males*)	0.32	0.078; 0.09-1.13
Diagnostic criteria: bone marrow (yes vs no*)	1.90	0.409; 0.41-8.72
Diagnostic criteria: EPP (yes vs no*)	0.98	0.983; 0.27-3.60
Diagnostic criteria: IE (yes vs no*)	0.83	0.748; 0.27-2.55
Plasmocytes		0.129
<10	1
10-60	7.95	0.053; 0.97-65.07
>60	3.18	0.415; 0.20-51.18
Caryotype (abnormal vs normal*)	2.52	0.358; 0.35-17.95
Anemia (yes vs no*)	2.00	0.182; 0.72-5.56
Renal disease (yes vs no*)	2.53	0.117; 0.79-8.09
Calcemia (yes vs no*)	6.58	0.006; 1.70-25.48	11.39	0.002; 2.45-52.88
Presence of lytic lesions (yes vs no*)	0.73	0.59; 0.23-2.33
B2 microglobulin		0.784
<3.5	1
3.5-5.3	0.48	0.546; 0.04-5.30
≥5.4	0.58	0.558; 0.09-3.62
Albumin (≥3.5 vs <3.5*)	2.28	0.220; 0.61-8.53
Staging		0.939
Stage 1	1
Stage 2	0.95	0.968; 0.06-15.34
Stage 3	1.32	0.804; 0.14-12.21
Transplant (yes vs no*)	1.07	0.915; 0.30-3.86
Consolidation treatment (yes vs no*)	0.76	0.730; 0.16-3.68
Progression (yes vs no*)	0.63	0.370; 0.23-1.73

Numbers in bold indicate significant p-values