Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jun 3;24(2):558. doi: 10.3892/mmr.2021.12197

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 5. — Effects of NAC on MeHg-induced changes in the expression levels of apoptosis-related proteins in PC12 cells. (A) Western blotting demonstrated the dynamic changes in (B) Bcl-2/Bax ratio, and the protein expression levels of (C) Bax and (D) Bcl-2 in PC12 cells pretreated with 250 µmol/l NAC for 60 min followed by exposure to 2.5 µmol/l MeHg for 48 h. (E) Western blotting demonstrated the dynamic changes in the protein expression levels of (F) pJNK and (G) JNK in PC12 cells pretreated with 250 µmol/l NAC for 60 min followed by exposure to 2.5 µmol/l MeHg for 48 h. Protein band intensity was analyzed after normalization to the corresponding GAPDH levels, and the relative ratios were analyzed after normalization to the corresponding control group. Data are presented as the mean ± SD, n=3. **P<0.01 and ***P<0.001 vs. control group; ^#P<0.05 and ^###P<0.001 vs. MeHg group. MeHg, methylmercury; DHA, docosahexaenoic acid; p, phosphorylated; NAC, N-acetyl-l-cysteine.