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. 2021 Jun 9;21:271. doi: 10.1186/s12887-021-02747-4

Table 2.

ORs of mildly and markedly increased ALTa for age and degree of obesity, stratified by sex

OR (99% CI, P value) OR (99% CI, P value)
Mildly increased ALT, n = 4461 Markedly increased ALT, n = 1245
Males Females Males Females
Age (years) 1.15 (1.13–1.18, < 0.001) 0.97 (0.95–0.99, 0.002) 1.34 (1.29–1.38, < 0.001) 1.06 (1.02–1.10, < 0.001)
Degree of obesity
 Class I obesity Ref Ref Ref Ref
 Class II obesity 1.52 (1.29–1.80, < 0.001) 1.57 (1.33–1.86 < < 0.001) 2.03 (1.60–2.58, < 0.001) 1.59 (1.15–2.20, < 0.001)
 Class III obesity 2.27 (1.82–2.82), < 0.001) 2.17 (1.75–2.70, < 0.001) 3.73 (2.77–5.02, < 0.001) 3.57 (2.52–5.06, < 0.001)

Abbreviations: ALT alanine aminotransferase, OR odds ratio, CI confidence interval, Ref reference group

a Compared to normal ALT group

ORs were adjusted for age and degree of obesity