Table 3.
Metabolic characteristics of individuals in the obesity cohort
| All individuals | Normal ALT | Mildly increased ALT | Markedly increased ALT | P value1 | P value2 | P value3 | |
|---|---|---|---|---|---|---|---|
| (n = 9223) | (n = 4789) | (n = 3527) | (n = 907) | ||||
| Impaired fasting glucose | 1897 (20.6) | 916 (19.1) | 718 (20.4) | 263 (29.0) | 0.163 | < 0.001 | < 0.001 |
| LDL-C | |||||||
| Borderline-high | 1902 (20.6) | 943 (19.7) | 758 (21.5) | 201 (22.2) | < 0.001 | < 0.001 | 0.015 |
| High | 1517 (16.5) | 671 (14.0) | 645 (18.3) | 201 (22.2) | |||
| Total cholesterol | |||||||
| Borderline-high | 2760 (29.9) | 1396 (29.2) | 1094 (31.0) | 270 (29.8) | < 0.001 | < 0.001 | 0.029 |
| High | 1183 (12.8) | 534 (11.2) | 491 (13.9) | 158 (17.4) | |||
| Low HDL-C | 1334 (14.5) | 554 (11.6) | 557 (15.8) | 223 (24.6) | |||
| Triglycerides | |||||||
| Borderline-high | 2126 (23.1) | 1094 (22.8) | 804 (22.8) | 228 (25.1) | < 0.001 | < 0.001 | < 0.001 |
| High | 2445 (26.5) | 956 (20.0) | 1105 (31.3) | 384 (42.3) | |||
Abbreviations: ALT alanine aminotransferase, TC total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, OR odds ratio, CI confidence interval
Differences between groups were assessed using the chi-square test
1 Comparison between mildly increased ALT and normal ALT group
2 Comparison between markedly increased ALT and normal ALT group
3 Comparison between markedly increased ALT and mildly increased ALT group