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. 2021 May 26;8:626328. doi: 10.3389/fmolb.2021.626328

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Copyright © 2021 Sun, Ge, Zhang, Yan, Wu, Ouyang, Wang, Ding, Zhang, Long, Liu, Shi, Zhou, Chen and Ye.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BARX1 and DLX4 predict poor prognosis in ccRCC and may promote epithelial–mesenchymal transition (EMT). (A) In the TCGA KIRC cohort, BARX1 and DLX4 highly expressed patients have poorer disease-specific survival (DSS). (B) In the TCGA KIRC cohort, BARX1 and DLX4 highly expressed patients have poorer overall survival (OS). (C) The prognostic nomogram of BARX1 or DLX4 for OS at 1, 3, and 5 years. (D) The gene set enrichment analysis (GSEA) of hallmark gene sets in the high-expression group of BARX1 or DLX4.