Fig. 7.

MiR-654-3p mimics inhibited apoptosis of ox-LDL treated HAECs through targeting AKT3. A AKT3 level evaluated by qRT-PCR in HAECs transfected with pc-AKT3 or pc-NC, and treated with ox-LDL for 24 h. B–D (B) Cell viability assessed by CCK-8 assay, C apoptosis evaluated by flow cytometry and D the levels of apoptosis-related proteins detected by Western blot in HAECs transfected with miR-NC, miR-654-3p mimics, pc-AKT3, or co-transfected with miR-654-3p mimics and pc-AKT3, and treated with ox-LDL for 24 h. * P < 0.05, ** P < 0.01