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. 2021 Jun 2;24(2):552. doi: 10.3892/mmr.2021.12191

Figure 4.

Figure 4.

HCG11 functions as a sponge of miR-875 in NSCLC cells. (A) Relative expression levels of miR-26a, miR-499a, miR-522, miR-224, miR-483, miR-214, miR-455, miR-534, miR-155, miR-105 and miR-875 in A549 cells following overexpression of HCG11. (B) Reverse transcription-quantitative PCR analysis of the expression levels of miR-875 in NSCLC tissues and adjacent normal tissues obtained from 85 patients. (C) Pearson correlation analysis of HCG11 and miR-875 expression in NSCLC tissues obtained from 85 patients. (D) Relative luciferase activity in 293T cells after co-transfection of WT or MUT HCG11 with miR-875-mimic or miR-NC. The specific binding site of miR-875 with HCG11 is shown in the top panel, based on StarBase. **P<0.01. NSCLC, non-small cell lung cancer; miR/miRNA, microRNA; NC, negative control; WT, wild-type; MUT, mutant; HCG11, HLA complex group 11.