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. 2021 May 26;12:684782. doi: 10.3389/fphys.2021.684782

TABLE 3.

Association between total daily PA (cpm) and MVPA (min/day) and metabolic health markers.

Biomarker Pacific
NZ European
All participants
Endocrine Total daily PA, difference (95% CI) per 100 units increase MVPA, difference (95% CI) per 10 units increase Total daily PA, difference (95% CI) per 100 units increase MVPA, difference (95% CI) per 10 units increase Total daily PA, difference (95% CI) per 100 units increase MVPA, difference (95% CI) per 10 units increase
HbA1c (mmol mol) −0.1 (−0.3, 0.2) 0.1 (−0.2, 0.4) 0.2 (0.0, 0.4)* −0.1 (−0.3, 0.1) 0.1 (0.0, 0.1) 0.0 (−0.2, 0.2)
Glucose (mmol L) 0.0 (−0.1, 0.0) −0.01 (−0.07, 0.05) 0.0 (0.0, 0.0) −0.03 (−0.06, 0.00) 0.0 (0.0, 0.0) −0.02 (−0.05, 0.01)
HOMA-IR −2.8 (−5.9, 0.4) −2.6 (−6.3, 1.0) 0.2 (−0.6, 0.9) −0.9 (−1.7, −0.1)* −0.9 (−2.2, 0.4) −1.5 (−2.9, −0.03)*
Leptin (pg ml) −729 (−1711, 251) −989 (−2090, 112) −26 (−826, 774) 31 (−794, 857) −304 (−917, 310) −267 (−920, 387)
Chol (mmol L) 0.0 (−0.1, 0.1) 0.05 (−0.03, 0.14) 0.0 (−0.1, 0.1) 0.03 (−0.03, 0.09) 0.0 (0.0, 0.1) 0.01 (−0.05, 0.07)
NEFA (mmol L) 0.0 (0.0, 0.1) −0.01 (−0.08, 0.05) 0.0 (0.0, 0.0) −0.03 (−0.06, 0.00) 0.0 (0.0, 0.0) 0.02 (0.00, 0.05)
Trig (mmol L) 0.0 (−0.1, 0.0) −0.01 (−0.08, 0.05) 0.0 (0.0, 0.0) −0.03 (−0.06, 0.00) 0.0 (−0.1, 0.0) −0.03 (−0.06, 0.01)
HDL (mmol L) 0.0 (0.0, 0.1) 0.03 (0.00, 0.07) 0.0 (0.0, 0.0) 0.04 (0.02, 0.06)*** 0.0 (0.0, 0.0) 0.03 (0.01, 0.06)**
LDL (mmol L) 0.0 (−0.1, 0.1) 0.03 (−0.06, 0.11) 0.0 (0.1, 0.1) 0.01 (−0.05, 0.06) 0.0 (0.0, 0.1) 0.00 (−0.06, 0.06)
Anthropometry
Weight (Kg) 0.4 (−1.2, 2.0) 0.49 (−1.49, 2.38) 0.3 (−0.6, 1.2) −0.12 (−1.03, 0.78) 0.3 (−0.5, 1.1) 0.12 (−0.77, 1.01)
Waist circumference (cm) −0.5 (−1.6, 0.6) −0.50 (−1.79, 0.79) 0.4 (−0.2, 1.1) −0.14 (−0.81, 0.52) 0.1 (−0.5, 0.6) −0.22 (−0.85, 0.41)
Hip circumference (cm) 0.1 (−0.9, 1.0) 0.22 (−0.90, 1.33) 0.1 (−0.6, 0.7) −0.04 (−0.70, 0.62) 0.0 (−0.5, 0.6) 0.09 (−0.49, 0.66)
Systolic blood pressure (mmHg) 1.1 (0.1, 2.2)* 0.45 (−0.79, 1.70) 0.1 (−1.0, 1.1) −0.30 (−1.34, 0.74) 0.4 (−0.3, 1.1) 0.00 (−0.79, 0.79)
Diastolic blood pressure (mmHg) 0.5 (−0.3, 1.4) −0.17 (−1.20, 0.86) −0.5 (−1.2, 0.3) −0.045 (−0.122, 0.031) −0.2 (−0.7, 0.4) −0.29 (−0.90, 0.33)
Heart rate (bpm) −1.1 (−2.3, −0.2) −1.83 (−3.19, −0.48)** −1.4 (−2.4, 0.4)** −1.21 (−2.26, −0.17)* −1.2 (−2.0, −0.4)** −0.14 (−2.26, −0.63)**

Total daily PA, ratio (95% CI) per 100 units increase MVPA, ratio (95% CI) per 10 units increase Total daily PA, ratio (95% CI) per 100 units increase MVPA, ratio (95% CI) per 10 units increase Total daily PA, ratio (95% CI) per 100 units increase MVPA, ratio (95% CI) per 10 units increase

Insulin (pmol/ml) 0.94 (0.88, 1.00) 0.92 (0.85, 0.99)* 1.00 (1.00, 1.00) 0.92 (0.90, 0.96)*** 1.00 (0.91, 1.00)* 0.95 (0.91, 0.98)**
CRP (mg L) 0.91 (0.82, 1.00) 0.96 (0.85, 1.10) 0.91 (0.82, 1.00)* 0.90 (0.83, 0.98)* 0.91 (0.82, 1.00)** 0.92 (0.87, 0.99)*

Total n = 272: Pacific n = 114 (n = 2 with missing deprivation data), NZE n = 158 (n = 1 with missing deprivation data). NZE, New Zealand European; PA, physical activity; MVPA, moderate to vigorous physical activity; HbA1c, fasting blood glycated haemoglobin; HOMA-IR, Homeostatic Model Assessment of Insulin Resistance; CRP, fasting C Reactive Protein; Chol, fasting blood total cholesterol; HDL, fasting High-density lipoprotein; LDL, fasting Low-density lipoprotein; NEFA, fasting non-esterified fatty acids; Trig, fasting triglycerides. All models adjusted for body fat% group, age and NZDep2013; further adjusted for ethnicity; *p < 0.05, **p < 0.01, ***p < 0.001; data has been log transformed (ln). Regression coefficients represent the change in the outcome per 100 cpm change in total daily PA and 10 min change in MVPA.