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. Author manuscript; available in PMC: 2021 Jun 9.
Published in final edited form as: Quant Biol. 2019 Jun;7(2):122–137. doi: 10.1007/s40484-019-0154-0

Figure 4. Example of a possibly reduced EPI (extended enhancer at chr19:6514600–6517600, promoter at chr19:6736700– 6738700) with mutation occurring within the motif of SP1 in the promoter region shown.

Figure 4.

The enhancer region is extended to be 3 kb in length and the promoter region is 2 kb. The estimated reduction likelihood of this EPI with the mutation is ranking top 0.2% of all the positive EPIs in the NHEK cell line.