Table 4.

Predicted potentially important TFs in enhancers involved in EPIs from SPEID in GM12878 and K562

	Potentially important TFs involved in EPI
Also in TargetFinder (GM12878)	SPI1, EBF1, SP1, IRF3, TCF12, BATF, PAX5, MEF2A, BCL11A, EGR1, SRF, IRF4, BHLHE40, PBX3, MEF2C, MAZ, NRF1, YY1, GABPA, ETS1, STAT1, NFYA
Unique in SPEID (GM12878)	CPEB1, HXC10, ARI3A, IRF1, IRF8, MNT, TBX15, TBX2, TBX5
Also in TargetFinder(K562)	CTCF, SRF, ATF3, MAZ, JUND, MEF2A, CEBPD, BHLHE40, NR2F2, EGR1, FOSL1, FOS, TAL1, JUNB, JUN, MAFK, E2F6, SP1, NFE2, NR4A1, GATA1, THAP1, SP2, RFX5, NRF1, USF2
Unique in SPEID (K562)	SP4, SP3, TFDP1, ZFX, WT1, KLF15, TBX1, ETV1, ZNF148, KLF6, HEN1, KLF14, TBX15, CLOCK, ELF2, PLAL1, PURA, ZNF740, AP2D, CPEB1, EGR2, FOXJ3, HES1, NR1I3, SREBF2, THA