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. Author manuscript; available in PMC: 2021 Jun 9.
Published in final edited form as: Oper Res. 2019 May 10;67(3):599–904. doi: 10.1287/opre.2018.1817

Figure 1:

Figure 1:

Action/Inaction boundary pb along with the solution to the first-order optimality condition, i.e., p¯, for (a) long-term focused planner (ρ1βr) and (b) short-term focused planner (ρ2 > βr). Gray arrows indicate the vector field defined in the system of ODE’s (5)–(6) when W (t) = 1, t ≥ 0. In panel (a) where ρ1 > βr, observe that the infimum of the set of drug qualities for which it is economical to prescribe the drug for some p > 0 is zero (i.e., q_=0). In addition, since p¯(q)=vc(p¯(q))/qvc(p¯(q)) converges to zero when p¯(q) is close to zero, p¯ is tangent to the q axis. In contrast, in panel (b) where ρ2 > βr, it is q_>0. Similar to panel (a), since ρ2 > 2β − 2r, the second derivative of vc to diverges infinity when p approaches to zero. This causes p¯(q_)=0 leading to the tangency of p¯ to the q-axis When ρ = ρ3, however however, the second derivative of vc is infinite at p = 0 and hence p¯(q_)>0. This case is shown in Fig. 9a in Appendix A.