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Germline usage and somatic hypermutation rate (SHM) of antibodies
| Antibody | V-H allele | J-H allele | CDR3 length (aa) | SHM (%) |
|---|---|---|---|---|
| JMB2002 Vκ | IGKV1-33*01 | IGKJ4*01 | 9 | 4.7 |
| JMB2002 VH | IGHV1-69*18 | IGHJ5*02 | 16 | 0.0 |
| CB6 Vκ | IGKV1-39*01 | IGKJ2*01 | 11 | 1.8 |
| CB6 VH | IGHV3-66*01 | IGHJ4*01 | 13 | 3.4 |
| Imdevimab (REGN10987) Vλ | IGLV2-14*03 | IGLJ3*02 | 10 | 4.5 |
| Imdevimab (REGN10987) VH | IGHV3-30*01 | IGHJ4*01 | 13 | 2.5 |
