Table 2.
Supercritical micronization conditions
| Run | T | V | t1 | t2 | P1 | P2 | Observation | Figure |
|---|---|---|---|---|---|---|---|---|
| 1 | 30 | 50 | 10 | 30 | 350 | 120 | Extra amount remained in the vial | – |
| 2 | 30 | 50 | 30 | 30 | 350 | 120 | Extra amount remained in the vial | – |
| 3 | 50 | 50 | 10 | 30 | 350 | 120 | Extra amount remained in the vial | – |
| 4 | 30 | 30 | 10 | 30 | 350 | 120 | No particles were formed | – |
| 5 | 30 | 30 | 10 | 30 | 350 | 100 | A few particles were formed | - |
| 6 | 30 | 30 | 10 | 60 | 350 | 100 | A few particles were formed | – |
| 7 | 30 | 30 | 10 | 30 | 350 | 80 | Big crystals were formed | 6a |
| 8 | 30 | 30 | 10 | 10 | 350 | 80 | Big crystals were formed | – |
| 9 | 50 | 30 | 10 | 30 | 350 | 80 | Nanoparticles were formed | 6b |
| 10 | 50 | 30 | 10 | 60 | 350 | 80 | No noticeable change | 6c |