Fig. 5.

Expression of key SARS-CoV-2 entry factors across 33 human tissues, 13 brain regions, and brain cell types/subpopulations. a Expression specificity of key SARS-CoV-2 entry factors in 33 tissues and b expression specificity of these genes in 13 brain regions using data from the GTEx database (see the “Materials and methods” section). c Co-expression of TMPRSS2, FURIN, and NRP1 vs. ACE2 in the brain regions. d Expression of key SARS-CoV-2 entry factors in the neuron cells. e Co-expression of TMPRSS2, FURIN, and NRP1 vs. ACE2 in the neuron. SCC, Spearman’s rank correlation coefficient. EC, entorhinal cortex. SFG, superior frontal gyrus. Excit neuron, excitatory neuron. Inhibit neuron, Inhibitory neuron