Extended Data Table 1 |.
Participant and RNS System details
| Participant number | 1 | 2 | 3 | 4 | 5 | |
|---|---|---|---|---|---|---|
| Age | 49 | 52 | 34 | 33 | 31 | |
| Gender | female | female | male | male | male | |
| Number of performed task blocks(1) | 2 | 3 | 4 | 4 | 4 | |
| RNS Neurostimulator model | RNS-300M | RNS-300M | RNS-320 | RNS-300M | RNS-300M | |
| Electrode 1 | Hemisphere | left | left | left | left | left |
| Implant orientation(2) | 0 | 0 | 0 | L | L | |
| Contact spacing | 3.5 mm | 3.5 mm | 10 mm | 10 mm | 10 mm | |
| Number of MTL channels | 2 | 2 | 1 | 2 | 2 | |
| Channel 1 localization(3) | Sub/Sub | Sub/Sub | ERC/PRC | HPP/Sub | HPP/HPP | |
| Channel 2 localization(3) | HPP/PWM | HPP/PRC | Sub/Sub | HPP/Sub | ||
| Electrode 2 | Hemisphere | right | left | right | right | right |
| Implant orientation(2) | 0 | L | 0 | L | O | |
| Contact spacing | 10 mm | 10 mm | 10 mm | 10 mm | 10 mm | |
| Number of MTL channels | 1 | 2 | 1 | 2 | 1 | |
| Channel 1 localization(3) | HPP/PRC | HPP/HPP | Sub/PRC | HPP/Sub | Sub/PWM | |
| Channel 2 localization(3) | HPP/HPP | Sub/Sub | ||||
1
Each block comprised about 15 min of the self-navigation task, followed by about 15 min of the observation task.
2
L, along the longitudinal axis of the hippocampus; O, orthogonally to the long axis of the hippocampus.
3
Localization of two electrode contacts (+/−) per bipolar recording channel. ERC, entorhinal cortex; HPP, hippocampus (CA1/CA2/CA3/DG); PRC, perirhinal cortex; PWM, parahippocampal white matter; Sub, subiculum.