Fig 3. Virus in blood of CHIKV-infected Hu-NSG mice with mosquito bite or needle injection.

CHIKV RNA copies/mL obtained from sera of humanized mice infected by mosquito bite (red) or subcutaneous injection (black) quantified by qRT-PCR. Unpaired t-tests were used to determine statistical significance between infection route at each time point. Asterisks indicate significance differences (* p<0.05; ** p<0.01; ***p<0.005). Error bars indicate SEM. Mice per group: n≥6.