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. Author manuscript; available in PMC: 2021 Jun 9.
Published in final edited form as: BJOG. 2018 Jun 25;125(11):1406–1413. doi: 10.1111/1471-0528.15292

Table 1.

Summary of intraclass correlation coefficient (ICC) estimates for neonatal outcomes across trials

Outcome Median (range) ICC Trials
Composite adverse neonatal outcome 1* 0.68 (0.52–0.71) 5–9,15,17,18,21
Composite adverse neonatal outcome 2** 0.65 (0.54–0.77) 4–9,15,17,18,20,21
Perinatal death 0.66 (0.17–0.80) 4,5,7,15,17,18,21
Respiratory distress syndrome 0.65 (0.50–0.74) 4–9,15,17,18,20,21
Bronchopulmonary dysplasia 0.51 (0.37–0.72) 5,17,18
Intraventricular haemorrhage 0.36 (0.13–0.45) 4,5,17
Necrotising enterocolitis 0.13 (0.12–0.14) 15,18
Sepsis 0.38 (0.35–0.47) 4,5,7,15,17,18
Admission to neonatal intensive care unit 0.79 (0.56–0.86) 4–9,15,17,18,21
Birthweight 0.79 (0.62–0.85) 4–9,15,17–21
Birthweight <2500 g 0.50 (0.37–0.71) 4–9,15,17–21
Birthweight <1500 g 0.71 (0.36–0.91) 4–9,15,17,18,20,21
*

Includes perinatal death, respiratory distress syndrome, bronchopulmonary dysplasia, intraventricular haemorrhage, necrotising enterocolitis, and sepsis.

**

Includes perinatal death, respiratory distress syndrome, intraventricular haemorrhage, and necrotising enterocolitis.