Fig. 6. In silico seeding from alternate sites.

Using the diffusion rate constant estimated by model fitting to empirical tau pathology spread, we estimated the distinct spreading patterns that arise after injection into alternate sites in the entorhinal area (A) and caudoputamen (B). Estimated spread is plotted as a heatmap in anatomical space with blue indicating regions with minimal estimated pathology and red indicating regions with elevated pathology. *Sites of injections.