REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Mouse Monoclonal anti-CD38 FITC	BD Biosciences	#340909
Mouse Monoclonal anti-HLADR PE	BD Biosciences	#347401
Mouse Monoclonal anti-CD4 BV421	BD Biosciences	#562424
Mouse Monoclonal anti-CD8 APCH7	BD Biosciences	#560179
Mouse Monoclonal anti-CD3 Alexa 700	BD Biosciences	#557943
Rat Monoclonal anti-CCR7 Alexa647	BD Biosciences	#557734
Mouse Monoclonal anti-CD21 PE	BD Biosciences	#555422
Mouse Monoclonal anti-CD27 APC	BD Biosciences	#337169
Mouse Monoclonal anti-CD45 Alexa 700	BD Biosciences	#560566
Mouse Monoclonal anti-CD56 PECF594	BD Biosciences	#564849
Mouse Monoclonal anti-HLADR BV605	BD Biosciences	#562845
Mouse Monoclonal anti-CD33 BV421	BD Biosciences	#562854
Mouse Monoclonal anti-CD141 BV711	BD Biosciences	#563155
Mouse Monoclonal anti-CD45RA PerCpCy5.5	BD Biosciences	#563429
Mouse Monoclonal anti-HLA ABC BV786	BD Biosciences	#740982
Mouse Monoclonal anti-CD86 PECF594	BD Biosciences	#562390
Mouse Monoclonal anti-PD1 BV605	BD Biosciences	#563245
Mouse Monoclonal anti-TCR gamma delta	BD Biosciences	#559878
Mouse Monoclonal anti-CD45RA PEefluor 610	ebiosciences	#61-0458-42
Mouse Monoclonal anti-Ki67 PercPe710	ebiosciences	#46-5698-82
Mouse Monoclonal anti-CD19 PC7	Beckman Coulter	#IM3628
Mouse Monoclonal anti-CD38 PercpCy5.5	Biolegend	#303522
Mouse Monoclonal anti-IgM Pacific Blue	Biolegend	#314514
Mouse Monoclonal anti-CD16 APC Cy7	Biolegend	#302018
Mouse Monoclonal anti-CD14 BV605	Biolegend	#301834
Mouse Monoclonal anti-CD1c PECy7	Biolegend	#331516
Mouse Monoclonal anti-CD40 PE	Biolegend	#334308
Mouse Monoclonal Lineage FITC	Biolegend	#348801
Mouse Monoclonal anti-CD57 PercPCy5.5	Biolegend	#359622
F(ab')2-Goat anti-Human IgD FITC	Invitrogen	#H15501
Mouse Monoclonal anti-CD123 APC	Miltenyi Biotec	#130-113-322
Mouse Monoclonal anti-NKG2A PEVio770	Miltenyi Biotec	#130-113-567
BD Cytofix/cytoperm fixation/permeabilization kit	BD Biosciences	# 554714
Biological Samples
French COVID-19 patients	French COVID cohort	clinicaltrials.gov NCT04262921
Swiss COVID-19 patients	Swiss cohort	Swiss ethics protocol ID: 2020-00620
Critical Commercial Assays
Human Magnetic Luminex Assay (CD163, ST2, and CD14, LBP)	R&D Systems	LXSAHM-2 kits
Human XL Cyt Disc Premixed Mag Luminex Perf Assay Kit	R&D Systems	LXSAHM-19 kit
48-Plex Bio-Plex Pro Human Cytokine	Bio-Rad	#12007283
CD177 ELISA Kit	ThermoFisher Scientific	EH80RBX5
Deposited Data
Raw and analyzed data	This paper	GEO code: GSE171110
Software and Algorithms
DIVA v6.2	BD Bioscences	https://www.bdbiosciences.com/en-us/instruments/research-instruments/research-software/flow-cytometry-acquisition/facsdiva-software
Bio-Plex Manager v6.1	Biorad	https://www.bio-rad.com/fr-fr/product/bio-plex-manager-software-standard-edition?ID=5846e84e-03a7-4599-a8ae-7ba5dd2c7684
hg19 human reference genome	This paper	https://www.ncbi.nlm.nih.gov/assembly/GCF_000001405.13/
STAR - v. 2.5.3ar, and quantified relative to annotation model hg19 - GENCODE Genes - release 19	N/A	[https://www.gencodegenes.org/human/release_19.html]
Sequence Analysis Viewer (SAV) version 2.1.8.
R (version 3.6)	The R Foundation for Statistical Computing, Vienna, Austria	https://www.r-project.org/
FlowJo v9	Treestar	https://www.flowjo.com/solutions/flowjo/downloads
SPICE v5.22	https://doi.org/10.1002/cyto.a.21015	(http://exon.niaid.nih.gov/spice)
Ingenuity Pathway software v.51963813.	Qiagen	Ingenuity Pathway Analysis (IPA) - QIAGEN Online Shop