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. 2020 Dec 31;16(3):885–890. doi: 10.1016/j.jds.2020.12.007

Table 1.

Univariate analysis of anamnestic variables associated with the complete healing of maxillary MRONJ.

Variable Category Outcome
Total p-value
Healing Not healing
Age (years) <75 25 4 29 0.512
≥75 21 4 25
Sex Male 15 2 17 0.437
Female 31 6 37
Stage 1, 2 34 3 37 0.202
3 12 5 17
Primary disease Osteoporosis 28 0 28 0.067
Malignancy 18 8 26
Type of agent BP 30 4 34 0.671
Dmab 16 4 20
Drug administration duration <4 years 27 4 31 0.838
≥4 years 19 4 23
Drug holiday No, <90 days 28 5 33 0.285
Yes, ≥90 days 18 3 21
DM No 42 6 48 0.301
Yes 4 2 6
Steroid administration No 33 7 40 0.781
Yes 13 1 14

MRONJ, medication-related osteonecrosis of the jaw; BP, bisphosphonate; Dmab, denosumab; DM, diabetes mellitus.