Table 1.
Variable | Category | Outcome |
Total | p-value | |
---|---|---|---|---|---|
Healing | Not healing | ||||
Age (years) | <75 | 25 | 4 | 29 | 0.512 |
≥75 | 21 | 4 | 25 | ||
Sex | Male | 15 | 2 | 17 | 0.437 |
Female | 31 | 6 | 37 | ||
Stage | 1, 2 | 34 | 3 | 37 | 0.202 |
3 | 12 | 5 | 17 | ||
Primary disease | Osteoporosis | 28 | 0 | 28 | 0.067 |
Malignancy | 18 | 8 | 26 | ||
Type of agent | BP | 30 | 4 | 34 | 0.671 |
Dmab | 16 | 4 | 20 | ||
Drug administration duration | <4 years | 27 | 4 | 31 | 0.838 |
≥4 years | 19 | 4 | 23 | ||
Drug holiday | No, <90 days | 28 | 5 | 33 | 0.285 |
Yes, ≥90 days | 18 | 3 | 21 | ||
DM | No | 42 | 6 | 48 | 0.301 |
Yes | 4 | 2 | 6 | ||
Steroid administration | No | 33 | 7 | 40 | 0.781 |
Yes | 13 | 1 | 14 |
MRONJ, medication-related osteonecrosis of the jaw; BP, bisphosphonate; Dmab, denosumab; DM, diabetes mellitus.