Table 4.
Details of the patients who did not achieve the healing of the maxillary MRONJ.
| Case | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
|---|---|---|---|---|---|---|---|---|
| Sex/Age | F/65 | M/77 | M/86 | F/81 | F/81 | F/68 | F/52 | F/60 |
| Stage | 3 | 3 | 2 | 3 | 3 | 2 | 2 | 3 |
| Primary disease | Malignancy | Malignancy | Malignancy | Malignancy | Malignancy | Malignancy | Malignancy | Malignancy |
| Type of drug | Dmab | BP | BP | Dmab | Dmab | BP | Dmab | BP |
| Drug administration period (y) | <4 | <4 | ≥4 | ≥4 | ≥4 | ≥4 | <4 | <4 |
| Steroid administration | Yes | No | No | No | No | No | No | No |
| DM | Yes | Yes | No | No | No | No | No | No |
| Periosteal reaction | No | No | No | Yes | Yes | No | No | No |
| Resection level | At the height of the apex | Above the apex | Above the apex | Above the apex | Above the apex | Above the apex | Above the apex | Below the apex |
| Residual necrotic bone | Yes | Yes | Yes | No | No | No | No | No |
| Sinus procedure | None | Open | None | Open | None | None | None | ESS |
MRONJ, medication-related osteonecrosis of the jaw; BP, bisphosphonate; Dmab, denosumab; DM, diabetes mellitus; F, female; M, male; ESS, endoscopic sinus surgery.