Table 2.
Risk factors for GIB after haplo-HSCT.
Variables | Univariate P value | Multivariate | ||
---|---|---|---|---|
HR | 95% | P value | ||
Age > 30 | 0.004 | 1.069 | 0.786–1.454 | 0.670 |
Male | 0.212 | |||
ABO mismatch | 0.147 | |||
Donor-recipient sex mismatch | 0.199 | |||
SOS | 0.038 | 6.105 | 1.471–25.341 | 0.013 |
DIC | 0.097 | 1.301 | 0.633–2.675 | 0.474 |
AKI | 0.000 | 3.115 | 2.110–4.599 | 0.000 |
CMV viremia | 0.148 | |||
Platelet counts < 30 × 109/L | 0.000 | 2.408 | 1.785–3.248 | 0.000 |
Viral hepatitis | 0.000 | 1.965 | 1.244–3.102 | 0.004 |
Gastrointestinal disease or bleeding before HSCT | 0.000 | 3.780 | 2.334–6.122 | 0.000 |
Diabetes mellitus | 0.153 | |||
Alcohol | 0.092 | 1.384 | 0.605–3.168 | 0.441 |
GIB gastrointestinal bleeding, SOS sinusoidal obstruction syndrome, DIC disseminated intravascular coagulation, AKI acute kidney injury, CMV cytomegalovirus, HSCT haematopoietic stem cell transplantation.