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. 2021 Jan 7;56(6):1341–1351. doi: 10.1038/s41409-020-01187-5

Table 2.

Risk factors for GIB after haplo-HSCT.

Variables Univariate P value Multivariate
HR 95% P value
Age > 30 0.004 1.069 0.786–1.454 0.670
Male 0.212
ABO mismatch 0.147
Donor-recipient sex mismatch 0.199
SOS 0.038 6.105 1.471–25.341 0.013
DIC 0.097 1.301 0.633–2.675 0.474
AKI 0.000 3.115 2.110–4.599 0.000
CMV viremia 0.148
Platelet counts < 30 × 109/L 0.000 2.408 1.785–3.248 0.000
Viral hepatitis 0.000 1.965 1.244–3.102 0.004
Gastrointestinal disease or bleeding before HSCT 0.000 3.780 2.334–6.122 0.000
Diabetes mellitus 0.153
Alcohol 0.092 1.384 0.605–3.168 0.441

GIB gastrointestinal bleeding, SOS sinusoidal obstruction syndrome, DIC disseminated intravascular coagulation, AKI acute kidney injury, CMV cytomegalovirus, HSCT haematopoietic stem cell transplantation.