Table 2.
Main clinical features of patients with Brunner's gland hamartoma: an overview of literature
| First author (year) | Sex | Age (years) | Complaint | Location | Shape | Size (cm) | Diagnosis | Treatment | Complication | Outcome |
|---|---|---|---|---|---|---|---|---|---|---|
| Walden (1998) | Male | 28 | Melena, exertional dyspnea | Duodenal bulb | Pedunculated polyp | 4.0 × 2.5 × 2.0 | Brunner's gland hamartoma | Endoscopic resection | Uneventful | Asymptomatic with 14 months follow-up |
| Rocco (2006) | Female | 58 | Epigastric discomfort | Duodenal bulb | Pedunculated polyp | 3.0 × 4.0 | Brunner's gland hamartoma | Endoscopic resection | Uneventful | Asymptomatic with 6 months follow-up |
| Gao (2004) | Male | 32 | Epigastric discomfort, melena | Duodenal bulb | Pedunculated polyp | 3.5 × 3.0 × 2.0 | Brunner's gland hamartoma | Surgical resection | Uneventful | Asymptomatic at postoperative period |
| Rana (2019) | Male | 76 | Vomiting, melena | Duodenal descending | Pedunculated polyp with multiple ulcers on surface | 10.0–12.0 × 3.5 × 1.5 | Brunner's gland hamartoma | Endoscopic resection | NA | NA |
| Peloso (2017) | Male | 72 | Epigastric pain, vomiting | Duodenal descending-horizontal junction | Broad-based lesion | 4.0 | Brunner's gland hamartoma | Polyp excision via duodenotomy | Uneventful | Asymptomatic at postoperative period |
| Akaki (2014) | Male | 26 | Melena, anemia | Gastroduodenal junction | Pedunculated polyp | 6.4 × 3.0 | Brunner's gland hamartoma | Distal gastrectomy | Uneventful | Asymptomatic with 1 year follow-up |
| Tan (2002) | Male | 70 | Melena, anemia | Duodenal descending | Pedunculated polyp | 10.0 × 2.0 × 1.5 | Brunner's gland hamartoma | Laparotomy via a transduodenal approach | Uneventful | Asymptomatic with 2 years follow-up |
| Martinez (2014) | Male | 60 | Epigastric discomfort, vomiting | Duodenal bulb | Subepithelial mass | 3.0 × 4.0 | Brunner's gland hamartoma | Surgical resection | NA | NA |
| Hizawa (2002) | Female | 62 | NA | Duodenal bulb | Broad-based lesion | 0.7 | Brunner's gland hamartoma | Endoscopic resection | Uneventful | NA |
| Female | 71 | Broad-based lesion | 1.8 | |||||||
| Male | 63 | Sessile polyp | 1.5 | |||||||
| Male | 65 | Sessile polyp with surface dimples | 1.5 | |||||||
| Male | 34 | Sessile polyp with surface dimples | 2.0 | |||||||
| Female | 36 | Pedunculated polyp | 2.0 | |||||||
| Kostalas (2016) | Female | 52 | Mildly deranged liver-function tests, weight loss | Duodenal bulb and descending | A solid mass | NA | Brunner's gland hamartoma | Pancreatoduodenectomy | NA | NA |
| Petersen (2008) | Female | 56 | Epigastric pain, nausea, vomiting, weight loss, anorexia | Pylorus-duodenal descending | Submucosal long tubular mass | 8.5 × 7.0 | Brunner's gland hamartoma | Billroth I procedure | Uneventful | Asymptomatic at postoperative period |
| Gourtsoyiannis (1990) | Male | 74 | Melena, weakness, dizziness | Duodenal descending | Pedunculated polyp | 5.0 × 3.0 × 4.0 | Brunner's gland hamartoma | Surgical resection | NA | NA |
| Takeuchi (2015) | Female | 52 | A sticking sensation when eating | Duodenal bulb | Pedunculated polyp | 5.0 × 3.0 | Brunner's gland hamartoma | Laparoscopic partial duodenectomy | NA | NA |
| Male | 67 | Epigastric discomfort | 6.0 × 3.5 | Laparoscopic and endoscopic tumor resection | ||||||
| Female | 52 | Asymptomatic | 3.5 × 2.7 | Laparoscopic partial duodenectomy | ||||||
| Kitagawa (2018) | Female | 64 | Anemia | Duodenal bulb | Pedunculated polyp | 7.0 | Brunner's gland hamartoma | Endoscopic mucosal resection | NA | NA |
| Jung (2013) | Male | 45 | Melena | Pyloric ring | Pedunculated polyp | 4.8 × 3.2 | Brunner's gland hamartoma | Piecemeal endoscopic mucosal resection | NA | No relapse with 5 months follow-up |
NA not available