Study	Reason for exclusion
Adrizzone 2006	Ineligible comparator group (AZA)
Ahluwalia 1992	Not a randomized control trial
Behrens 2013	No control group
Dignass 2018	No control group (both groups received 1000 mg mesalamine a day)
Fiorino 2019	The study drug was not pure 5‐ASA, but also contained sodium hyaluronate
Gross 2011	Ineligible comparator group (Budesonide)
Irvine 2008	Not a randomized control trial
Kamm 2009	Not a randomized control trial
Levine 2017	Not an oral 5‐ASA formulation
Mahmood 2005	Not an oral 5‐ASA formulation
Paoluzi 2002	No control group
Park 2018	Maintenance study
Pruitt 1991	Not a randomized control trial
Rubin 2017	Compares once‐daily budesonide to placebo in people who are refractory to 5‐ASA treatment
Safdi 1997	Not an oral 5‐ASA formulation
Suzuki 2017	Not an induction trial
Turner 2017	A pediatric study
Vecchi 2001	Not an oral 5‐ASA formulation
Vernia 2000	No control group
Ye 2018	No control group (both groups received same oral regimen)
Yoshimura 2018	No control group