Table 2.
Outcome of volume assessment and BID exam of study population during first 5 days after surgery.
| Study day [mean ± SD, (median)] | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 |
|---|---|---|---|---|---|
| Volume assessment | |||||
| CLIa,% | 34.8 ± 33.6 (30.7) | 54.2 ± 30.5 (52.1) | 50.2 ± 23.9 (48) | 40.6 ± 20.2 (40.2) | 23 ± 22 (22) |
| SCVO2%b | 77.2 ± 10.1 (78.6) | 75.3 ± 7.5 (75.2) | 71.7 ± 6 (72.2) | 74 ± 6.9 (74.5) | 75.7 ± 8.5 (74.1) |
| Daily fluid balancec, ml | 554.3 ± 996.6 (510) | 656.5 ± 1021.5 (667) | 346.5 ± 1216 (469.5) | 224.5 ± 796.9 (456) | 152.1 ± 998.9 (226.5) |
| BID data | |||||
| Intracellular water (ICW) | 22.4 ± 21 (20.7) | 21.1 ± 4.3 (21.1) | 20.8 ± 4.5 (20.7) | 20.7 ± 3.9 (20.5) | 20.4 ± 4.6 (20.5) |
| Extracellular water (ECW) | 15 ± 14.1 (14.5) | 17.2 ± 3 (17.1) | 14.5 ± 3.2 (14.4) | 14.2 ± 3.2 (14.3) | 14.2 ± 3.2 (14.6) |
| Total body water (TBW) | 37.4 ± 35.1 (35.7) | 38.3 ± 7 (37.7) | 35.4 ± 7.4 (34.9) | 34.9 ± 6.8 (35.3) | 34.6 ± 7.8 (35.3) |
| ECW ratio (ECW/TBW) | 0.4 ± 0.19 (0.35) | 0.46 ± 0.03 (0.45) | 0.41 ± 0.03 (0.42) | 0.39 ± 0.01 (0.39) | 0.4 ± 0.01 (0.4) |
| Overhydrationd | 136 (71.6) | 135 (71.1) | 106 (55.8) | 109 (59.2) | 81 (45) |
| Phase angle AT 50 kHz | 3.8 ± 3.42 (3.9) | 4.11 ± 1.47 (4) | 3.75 ± 1.25 (3.72) | 3.67 ± 1.22 (3.6) | 3.57 ± 1.06 (3.5) |
aCapillary leak index was defined as C-reactive protein (CRP) over serum albumin ratio which was multiplied by 100, as described in Malbrain et al.11.
bCentral venous oxygen saturation (SCVO2) was measured via indwelling central line of the patients.
cDaily fluid balance was defined as the difference between daily total intake including both intravenous and enteral fluid administered, blood products or medications and total output including all losses through urinary, gastrointestinal, or other drainage tubes.
dOverhydration is defined as the case where the value of ECW ratio (ECW/TBW) is above 0.39013–15.