Table 3.

Multivariate analyses of independent risk factors for the occurrence of (A) postoperative morbidities and (B) in-hospital mortality.

Variable	Odds ratio	95% CI	p-value
(A) Postoperative morbidities
ECW ratio at Day 1	1.161 × 107	0.001–1.150 × 1017	0.166
ECW ratio at Day 2	1.961	0.000–3.5 × 107	0.937
SOFA score at ICU admission	1.163	1.038–1.304	0.009
Overhydration at Day 3	3.151	1.474–6.737	0.003
Overhydrationa at Day 5	1.814	0.682–4.825	0.233
(B) In-hospital mortality
ECW ratio at Day 1	119.081	0.000–2.643 × 1013	0.720
ECW ratio at Day 2	154.035	0.000–8.814 × 1010	0.624
SOFA score at ICU admission	1.182	1.056–1.323	0.004
Overhydrationa at Day 3	2.040	1.007–4.590	0.045

Postoperative morbidities was defined as the occurrence of morbidities as grade III or more according to the Clavien–Dindo classification¹²; Grade I complication means any deviation from the normal postoperative course without the need of any pharmacologic treatment or interventions, Grade II complications are defined as the cases that require pharmacologic treatment, total parenteral nutrition, or blood transfusion, Grade III complications are any cases that require endoscopic, radiologic, or surgical interventions, Grade IV complications are defined as life-threatening morbidities, Grade V complications represent the death of a patient.

^aOverhydration is defined as the case where the value of ECW ratio (ECW/TBW) is above 0.390^13–15.