Table 2.

Multivariate Cox proportional hazards model of all patients

Variable	HR (95% CI)	P value
TLS Present	0.51 (0.27 to 0.97)	0.04
Age	1.00 (0.97 to 1.02)	0.75
Stage 4 disease	1.51 (0.67 to 3.42)	0.32
Intratumoral CD8 density	0.71 (0.34 to 1.49)	0.37
Curative-intent resection	0.53 (0.24 to 1.17)	0.12

Includes all patients (n=64) with metastatic skin lesions. Model stratified by patient sex to control for Schoenfeld residual <0.01.

TLS, tertiary lymphoid structure.