Table 2.
Region-of-Interest (ROI) measures by menopausal stage group.
| PRE | PERI | POST | |
|---|---|---|---|
| ATP/PCr measures | |||
| Superior temporal gyrus | 1.11 (0.05) | 1.18 (0.03) | 1.26 (0.03)* |
| Adjusted by APOE status | 1.14 (0.04) | 1.18 (0.03) | 1.24 (0.02)* |
| Middle temporal gyrus | 1.09 (0.04) | 1.13 (0.03) | 1.20 (0.02)* |
| Adjusted by APOE status | 1.10 (0.03) | 1.14 (0.02) | 1.19 (0.02)* |
| Inferior temporal gyrus | 1.07 (0.04) | 1.11 (0.02) | 1.13 (0.02)* |
| Adjusted by APOE status | 1.07 (0.03) | 1.10 (0.02) | 1.14 (0.02)* |
| Inferior parietal lobule | 0.77 (0.06) | 0.76 (0.05) | 0.83 (0.04) |
| Adjusted by APOE status | 0.78 (0.04) | 0.75 (0.03) | 0.83 (0.03)* |
| Amyloid-β load | |||
| AD-mask SUVR | 1.01 (0.12) | 1.20 (0.06) | 1.27 (0.07) |
| Adjusted by APOE status | 1.00 (0.09) | 1.21 (0.06) | 1.29 (0.06)* |
| AD-mask SUVR by APOE-4 status | |||
| APOE-4− | 0.94 (0.12) | 1.14 (0.07) | 1.32 (0.07)* |
| APOE-4+ | 1.07 (0.12) | 1.32 (0.11)* | 1.25 (0.08)* |
APOE-4−, APOE-4 non-carriers; APOE-4+, APOE-4 carriers; PERI, peri-menopausal group; POST, post-menopausal group; PRE, pre-menopausal group; SUVR, standardized uptake value ratio to cerebellar gray matter PiB uptake.
Values are means (SE), unless otherwise specified.
*Different from PRE, p < 0.05.