Table 2.

List of intercellular junction genes differentially expressed in rat retina and/or brain microvessels vs. retina and brain tissue samples.

Symbol	RMVs	RT	RMVs versus RT		BMVs	BT	BMVs versus BT		RMVs versus BMVs
			FC	adj. P			FC	adj. P	FC	adj. P
Ocln	9.7 ± 0.17	6.4 ± 0.13	9.8	2E−27	10.8 ± 0.04	7.4 ± 0.06	10.7	6E−29	− 2.1	8E−10
Cldn5	13.1 ± 0.1	9.4 ± 0.13	12.1	7E−34	13.4 ± 0.01	10.3 ± 0.04	8.4	3E−31	− 1.2	2E−02
Jam2	12 ± 0.05	10.9 ± 0.02	2.1	5E−20	12.2 ± 0.04	10.2 ± 0.02	4.0	8E−32	− 1.1	8E−03
Cdh5	11.4 ± 0.1	7.1 ± 0.06	21.1	2E−37	12 ± 0.01	8.1 ± 0.11	15.6	8E−36	− 1.5	1E−05
ZO-1	11.6 ± 0.09	10.8 ± 0.03	1.7	3E−15	12.2 ± 0.03	10.6 ± 0.03	3.1	3E−28	− 1.5	4E−12
Ctnna1	8.6 ± 0.12	8.1 ± 0.07	1.4	1E−05	9.3 ± 0.01	8.1 ± 0.03	2.3	3E−16	− 1.6	9E−08
Cx37	10.1 ± 0.07	6.9 ± 0.07	9.2	6E−27	10.8 ± 0.08	6.9 ± 0.10	14.8	4E−31	− 1.6	2E−05
Cx43	9.0 ± 0.10	7.4 ± 0.36	3.0	2E−08	10.9 ± 0.06	11.5 ± 0.02	− 1.5	5E−02	− 3.7	5E−09
Cx40	6.9 ± 0.05	6.2 ± 0.09	1.6	5E−06	8.6 ± 0.09	6.1 ± 0.13	5.7	2E−25	− 3.2	7E−18

Results are mean ± SEM of log₂ transformed microarray intensity values (n = 6). RMVs, retinal microvessels; RT, retinal tissue; BMVs, brain microvessels; BT, brain tissue; FC, fold change; adj. P, false discovery rate adjusted p value; Ocln, occluding; Cldn5, claudin 5; Jam2, junctional adhesion molecule 2; Cdh5, VE-cadherin; ZO-1, zonula occludens protein 1; Ctnna1, catenin α1; Cx, connexin.