Table 1.

Crystal structures of PI3K-α and PKC-η co-crystalized with different ligands were downloaded from PDB.

S. No	Crystal structures (PDB ID)	Ligand	Resolution	Year
PI3K-α
1	4A55	PIK-108	3.5 Å	2011
2	4JPS	(2S)-N ~ 1 ~ -{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide	2.20 Å	2014
3	5DXT	(2S)-2-({2-[1-(propan-2-yl)-1H-1,2,4-triazol-5-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl}oxy)propanamide	2.25 Å	2016
4	5UBR	1-[4-(3-{4-amino-5-[1-(oxan-4-yl)-1H-pyrazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-7-yl}phenyl)piperazin-1-yl]ethan-1-one	2.40 Å	2017
5	6PYS	(3S)-3-benzyl-3-methyl-5-[5-(2-methylpyrimidin-5-yl)pyrazolo[1,5-a]pyrimidin-3-yl]-1,3-dihydro-2H-indol-2-one	2.19 Å	2019
6	7K6M	2,2-difluoroethyl (3S)-3-{[2'-amino-5-fluoro-2-(morpholin-4-yl)[4,5'-bipyrimidin]-6-yl]amino}-3-(hydroxymethyl)pyrrolidine-1-carboxylate	2.41 Å	2021
PKC-η
1	3TXO	2-methyl-N ~ 1 ~ -[3-(pyridin-4-yl)-2,6-naphthyridin-1-;[yl]propane-1,2-diamine	2.05 Å	2011
2	3TXO	Staurosporine	2.05 Å	2011