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. 2021 Jun 9;11:12176. doi: 10.1038/s41598-021-88052-7

Figure 2.

Figure 2

Correlation between pathway dysregulation and brain HIV RNA load in three brain regions of patients with HIV. (AC) Scatter (volcano) plots that depict differentially regulated pathways by GSEA between high brain HIV RNA load (HIV H) and low brain HIV RNA load (HIV L) in (A) the basal ganglia, (B) white matter, and (C) the frontal cortex. NES, running normalized enrichment score. Tables for each brain region show representative downregulated and upregulated pathways. Pathways with substantial overlap are omitted from these lists. Complete lists are shown in Supplementary Tables S3-6.