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. 2021 Jun 9;11:12127. doi: 10.1038/s41598-021-91393-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Metabolic normalization precedes resolution of systemic inflammation. (A) Comparison of the p-values of the metabolic and inflammatory markers at 3 and 6 months post-surgery versus preoperatory values. The dashed line represents the cut-off for statistical significance (p-value = 0.05). (B) Median values at each time point after normalization, represented as the magnitude of change in each variable. IFN: Interferon, IL: Interleukin, TNF: Tumor Necrosis Factor. HOMA-IR: Homeostatic Model Assessment for Insulin Resistance, Chol: Total cholesterol, hs-CRP: high sensitivity C-reactive protein. This figure was made with the help of Tidyverse and Hmisc packages in R software.