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. 2021 Jun 9;11:12139. doi: 10.1038/s41598-021-91573-w

Table 1.

Baseline characteristics of total participants.

N = 83
Number %
Sex
Male 40 48.2
Female 43 51.8
Alcohol drinking
Yes 49 59.0
No 34 41.0
Smoking
Yes 17 20.5
No 66 79.5
Motion sickness
Yes 18 21.7
No 65 78.3
Mean SD
Age 38.53 11.80
Baseline SSQ 23.76 26.29
Nausea 16.09 21.89
Oculomotor 20.82 21.60
Disorientation 27.67 36.08
Total 23.76 26.29
Psychological scales
STAI-X-1 46.95 10.01
NRS 55.52 24.17
PSS-10 25.93 4.50
PANAS—total 22.55 9.80
PANAS—positive affect 13.89 6.32
PANAS—negative affect 8.69 6.64
SDS 15.08 6.73
STAI-X-2 47.82 10.00
EQ-5D-5L 6.47 1.63
Physiological parameters
EMG (µV) 2.27 1.33
Skin conductance (µS) 0.56 0.59
Skin temperature (℃) 33.03 1.48
Respiration amplitude 42.15 6.87
HR/BVP 29.70 0.09
HR from IBI 70.54 11.94
VLF total 61.95 47.84
LF total 93.94 89.80
HF total 79.55 84.29
HRV total 247.82 201.18
LF/HF 2.15 2.20
EKG IBI 848.96 154.97
NN50 62.40 72.16
SDNN 59.00 62.14
RMSSD 76.81 104.49
Ophthalmologic parameters
Subjective visual fatigue 4.06 3.78
TBUT 4.97 2.64
Maximal pupil diameter 4.72 1.02
Minimal pupil diameter 2.54 0.93
Pupil constriction percentage − 43.36 20.81
Latency of papillary response 0.22 0.05
Near point of accommodation 7.84 4.51
Near point of convergence 7.45 5.12
Inter-blink interval 29.83 16.29
Otologic parameters
VHIT 1.05 0.07
SOT (equilibrium) 81.30 5.30
SOT (somatosensory) 0.98 0.02
SOT (visual) 0.88 0.06
SOT (vestibular) 0.72 0.11
SOT (preference) 1.04 0.05

SD standard deviation, SSQ Simulator Sickness Questionnaire, STAI State-Trait Anxiety Inventory, NRS Numeric Rating Scale, PSS-10 Perceived Stress Scale, PANAS Positive and Negative Affect Schedule, SDS Sheehan Disability Scale, EQ-5D-5L Five-level version of EQ-5D, EMG electromyography, HR/BVP heart rate/blood vessel pressure, IBI inter-beat interval, VLF very low frequency band, LF low frequency band, HF high frequency band, HRV heart rate variability, NN50 number of interval differences of successive normal-to-normal (NN) intervals greater than 50 ms, SDNN standard deviation of NN, RMSSD the root mean square of the successive differences, TBUT tear breakup time, VHIT video head impulse test, SOT sensory organization test.