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. 2021 Jun 9;12:3503. doi: 10.1038/s41467-021-23698-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a mVC hierarchical protein grouping where each row represents a single protein group (887 total) and each column represents a single mVC (94 total). Metadata for encoded AMGs, estimated taxonomy, source environment and number of protein groups per mVC is shown. Clades respective of b, c, and d are depicted by colored dotted lines. Genome alignments of b seven divergent Myoviridae mVCs encoding dsrC from diverse environments, c four divergent Myoviridae mVCs encoding soxYZ from diverse environments, and d four divergent Siphoviridae mVCs encoding dsrA and dsrC from hydrothermal environments. For the genome alignments, each black line represents a single genome and arrows represent predicted proteins, which are colored according to VIBRANT annotations; genomes are connected by lines representing tBLASTx similarity. e Map of geographic distribution of 15 mVCs depicted in b, c, and d annotated with respective clade, source environment, and taxonomic family.