Table 1.
Variant inflation/deflation characteristics by categories of MAF.
| Deflation | Approx. no inflation | Inflation | ||||||
|---|---|---|---|---|---|---|---|---|
| MAF category | # variants | (0, 0.9] | (0.9, 0.95] | (0.95, 0.99] | (0.99, 1.01] | (1.01, 1.05] | (1.05, 1.1] | (1.1, 1.24] |
| BMI | ||||||||
| [0.00102, 0.01] | 13151242 | 14.47% | 48.96% | 7.25% | 4.39% | 19.74% | 4.93% | 0.25% |
| (0.01, 0.05] | 5497411 | 0.99% | 63.77% | 6.34% | 4.14% | 24.23% | 0.53% | – |
| (0.05, 0.2] | 3393012 | – | 19.37% | 27.68% | 23.15% | 29.80% | <0.01% | – |
| (0.2, 0.5] | 3318076 | – | 0.16% | 11.40% | 70.64% | 17.80% | – | – |
| HGB | ||||||||
| [0.00134, 0.01] | 11140793 | – | 64.79% | 9.05% | 3.04% | 19.97% | 3.15% | – |
| (0.01, 0.05] | 6047232 | – | 64.41% | 9.45% | 5.29% | 20.81% | 0.04% | – |
| (0.05, 0.2] | 3704075 | – | 19.59% | 29.49% | 23.54% | 27.38% | – | – |
| (0.2, 0.5] | 3358855 | – | 0.20% | 12.08% | 73.15% | 14.58% | – | – |
In each of the analyses (BMI and HGB), for each allele frequency category we provide the number of variants in this category, and from these, the proportion of variants with computed λvs in each of multiple categories of inflation/deflation values.