Table 1.

Clinical information of pregnant MS patients and healthy controls.

	Ex vivo
	RRMS, no PP relapse	RRMS, PP relapse	HC
Number of individuals	13	6	12
Median maternal age (range)	33.3 (26.8–33.8)	32.1 (29.8–33.7)	33.3 (27.7–34.1)
Median EDSS third trimester (range)	1.5 (0.0–2.0)	1.0 (0.0–2.0)	N.A
Median EDSS postpartum (range)	1.0 (0.0–2.0)	1.8 (1.0–4.5)	N.A
Nullipara	4	1	9
Caesarean section	2	0	1
(Pre)eclampsia	0	0	0
Median gestation (weeks, range)	40 (39.0–41.0)	38.0 (38.0–39.0)	39.0 (37.0–40.0)

	In vitro
	RRMS, no PP relapse	RRMS, PP relapse	HC
Number of individuals	8	3	5
Median maternal age	31.9 (26.8–37.3)	31.5 (N.A)	27.9 (27.2–27.9)
Median EDSS third trimester (range)	1.5 (0.0–2.0)	2.0 (0.0–2.0)	N.A
Median EDSS postpartum (range)	1.0 (0.0–2.0)	2.0 (1.5–3)	N.A
Nullipara	5	2	1
Caesarean section	2	0	0
(Pre)eclampsia	0	0	0
Median gestation (weeks, range)	39.5 (38.0–41.0)	39 (38.0–40.0)	38.6 (34.0–42.0)

Information on cesarean section, nullipara, pre(eclampsia) and gestational period was missing for 1 RRMS patient with a PP relapse.

PP postpartum.