Fig. 1. Virological, clinical and cytokines/chemokines characteristics in LDs and SDs.

a The Kaplan–Meier method was used to estimate the positive rate of viral RNA, and the two-sided log-rank test was applied to evaluate the significance difference of the duration of viral shedding in the LDs (n = 12) and SDs (n = 38). b The C-reactive protein (CRP) values obtained from clinical records of LDs (n = 12) and SDs (n = 38) and erythrocyte sedimentation rate (ESR) values obtained from clinical records of LDs (n = 10) and SDs (n = 38). The box plots show the median (middle line) and the first and third quartiles (boxes), whereas the whiskers show 1.5× the interquartile range (IQR) above and below the box. Non-paired two-tailed student t test was performed. c Samples from HDs (n = 22), LDs (n = 12) and SDs (n = 38) were collected, and assays were performed to measure the concentrations of 48 cytokines/chemokines, of which 20 with statistically significant are shown. Y axis represents the cytokine concentration (pg/ml). The box plots show the median (middle line) and the first and third quartiles (boxes), whereas the whiskers show 1.5× the IQR above and below the box. One-sided Wilcoxon rank-sum test are performed. Source data are provided as a Source Data file.