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. 2021 Jun 9;12:3501. doi: 10.1038/s41467-021-23621-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a Enriched GO pathways of COVID-19 groups in memory CD8⁺ T cells (top 2 columns: DEGs between LDs and SDs, bottom 4 columns: DEGs for SDs and LDs compared to HDs. Pathway enriched by SDs upregulated genes are labeled in red. The color intensity indicates the enrichment p values and the point size indicates the ratio of gene enrich in each pathway. b Hierarchical clustering of expression of DEGs in memory CD8⁺ T cells at sample level. The color intensity indicates the relative expression of each gene. c, d The clonal status percentage of T cells and that at each cell type resolution in three groups. e The percentage of selected clonal types in three groups. Source data are provided as a Source Data file.