Table 1.
Author | Vascular type | MVI status | Number | 5-year OS (%) | p-value | 5-year DFS (%) | p-value | Published year |
---|---|---|---|---|---|---|---|---|
Kang et al. (7) | MI+MPVI | NVI | 212 | 90 | 0.001 | 75 | <0.001 | 2020 |
MI | 64 | 78 | 45 | |||||
MPVI | 36 | 55 | 25 | |||||
Song et al. (43) | MI+MPVI+MHVI | NVI | 206 | NA | NA | 49.3 | <0.001 | 2019 |
MVI | 94 | NA | 28.2 | |||||
Wang et al. (34) | MI+MPVI+MHVI | NVI | 34 | 78.3 | <0.001 | 45.7 | <0.001 | 2019 |
MVI | 30 | 48.9 | 7.5 | |||||
Nitta et al. (33) | MI+MHVI | NVI | 148 | 66.1 | <0.001 | 28.6 | <0.001 | 2019 |
MVI | 117 | 38.4 | 15.8 | |||||
Han et al. (9) | NA | NVI-N* | 145 | 64 | <0.05 | 41 | <0.05 | 2018 |
MVI-N* | 158 | 55 | 30 | |||||
Han et al. (9) | NA | NVI-W# | 300 | 78 | <0.01 | 58 | <0.01 | 2018 |
MVI-W# | 192 | 66 | 48 | |||||
Hwang et al. (31) | NA | NVI | 1720 | 80.9 | <0.001 | 47.1 | <0.001 | 2015 |
MVI | 236 | 61.2 | 30.9 | |||||
Banerjee et al. (44) | NA | NVI | 111 | 78 | <0.001 | 61 | <0.001 | 2015 |
MVI | 44 | 55 | 33 | |||||
Yamashita et al. (18) | MPVI+MHVI+MBDI | NVI | 106 | 87 | 0.26 | 72 | <0.001 | 2012 |
MVI | 43 | 67 | 44 | |||||
Lim et al. (14) | NA | NVI | 197 | 61.3 | <0.001 | NA | NA | 2011 |
MVI | 44 | 36.6 | NA |
NA, not available; MI, microvessel invasion; MHVI, microscopic hepatic vein invasion; MPVI, microscopic portal vein invasion; MBDI, microscopic bile duct invasion; N*, narrow surgical margin <1 cm; W#, wide surgical margin ≥1 cm.