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. 2021 May 27;11:691354. doi: 10.3389/fonc.2021.691354

Table 1.

MVI prognostic capability in HCC after liver resection.

Author Vascular type MVI status Number 5-year OS (%) p-value 5-year DFS (%) p-value Published year
Kang et al. (7) MI+MPVI NVI 212 90 0.001 75 <0.001 2020
MI 64 78 45
MPVI 36 55 25
Song et al. (43) MI+MPVI+MHVI NVI 206 NA NA 49.3 <0.001 2019
MVI 94 NA 28.2
Wang et al. (34) MI+MPVI+MHVI NVI 34 78.3 <0.001 45.7 <0.001 2019
MVI 30 48.9 7.5
Nitta et al. (33) MI+MHVI NVI 148 66.1 <0.001 28.6 <0.001 2019
MVI 117 38.4 15.8
Han et al. (9) NA NVI-N* 145 64 <0.05 41 <0.05 2018
MVI-N* 158 55 30
Han et al. (9) NA NVI-W# 300 78 <0.01 58 <0.01 2018
MVI-W# 192 66 48
Hwang et al. (31) NA NVI 1720 80.9 <0.001 47.1 <0.001 2015
MVI 236 61.2 30.9
Banerjee et al. (44) NA NVI 111 78 <0.001 61 <0.001 2015
MVI 44 55 33
Yamashita et al. (18) MPVI+MHVI+MBDI NVI 106 87 0.26 72 <0.001 2012
MVI 43 67 44
Lim et al. (14) NA NVI 197 61.3 <0.001 NA NA 2011
MVI 44 36.6 NA

NA, not available; MI, microvessel invasion; MHVI, microscopic hepatic vein invasion; MPVI, microscopic portal vein invasion; MBDI, microscopic bile duct invasion; N*, narrow surgical margin <1 cm; W#, wide surgical margin ≥1 cm.