Table 2.

Immunomarking for the Profile of Tumor Proliferation (ki67) and Cell Death (TUNEL) in Biopsy Samples from Patients with Breast AC Stratified According to the Molecular Subtype Luminal A and Luminal B

Molecular subtype						Logistic regression model
Markes	Luminal A		Luminal B		p-Valor	P	OR	(CI 95%)
Ki-67
Primary tumor
0%	3	30.00%	4	14.30%		-	-	-	-
1-25%	7	70.00%	13	46.40%		-	-	-	-
25-50%	0	0.00%	6	21.40%	0.25	-	-	-	-
51-75%	0	0.00%	2	7.10%		-	-	-	-
76-100%	0	0.00%	3	10.70%		-	-	-	-
Peritumoral area
0%	0	0.00%	4	57.10%		-	-	-	-
1-25%	0	0.00%	3	42.90%		-	-	-	-
25-50%	0	0.00%	0	0.00%	1	-	-	-	-
51-75%	0	0.00%	0	0.00%		-	-	-	-
76-100%	0	0.00%	0	0.00%		-	-	-	-
Lymph node metastasis
0%	0	0.00%	2	10.00%		-	-	-	-
1-25%	4	80.00%	10	50.00%		-	-	-	-
25-50%	0	0.00%	6	30.00%	0.484	-	-	-	-
51-75%	0	0.00%	1	5.00%		-	-	-	-
76-100%	1	20.00%	1	5.00%		-	-	-	-
TUNEL						-	-	-	-
Primary tumor
0%	1	12.50%	1	3.40%		-	-	-	-
25-50%	1	12.50%	2	6.90%	0.472	-	-	-	-
51-75%	0	0.00%	4	13.80%		-	-	-	-
76-100%	6	75.00%	22	75.90%		-	-	-	-
Peritumoral area
0%	1	12.50%	1	4.30%		-	-	-	-
25-50%	1	12.50%	0	0.00%	0.007*	-	-	-	-
51-75%	3	37.50%	1	4.30%		0.02	21	1.613	273.34
76-100%	3	37.50%	21	91.30%		-	-	-	-
Lymph node metastasis
0%	1	11.10%	1	4.80%		-	-	-	-
1-25%	1	11.10%	0	0.00%	0.174	-	-	-	-
51-75%	0	0.00%	6	28.60%		-	-	-	-
76-100%	7	77.80%	14	66.70%		-	-	-	-

Pearson's chi-square test or Fisher's exact test, p<0,05