Table 5.

Immunomarking for the Profile of Tumor Proliferation (Ki67) and Cell Death (TUNEL) in Relation to the Presence of Recurrence in Biopsy Samples from Patients with Breast Cancer

Markers	Recurrence (n/%)
	Yes	No	p-Value
Ki67 (score)
Primary tumor
0%	7 (22.6)	0 (0.0)
1-25%	15 (48.4)	5 (71.4)
25-50%	4 (12.9)	2 (28.6)	0.38
51-75%	2 (6.5)	0 (0.0)
76-100%	3 (9.7)	0 (0.0)
Peritumoral area
0%	2 (50.0)	2 (66.7)
1-25%	2 (50.0)	1 (33.3)
25-50%	-	-	1
51-75%	-	-
76-100%	-	-
Lymph node metastasis
0%	2 (9.5)	0 (0.0)
1-25%	10 (47.6)	4 (100.0)
25-50%	6 (28.6)	0 (0.0)	0.547
51-75%	1 (4.8)	0 (0.0)
76-100%	2 (9.5)	0 (0.0)
TUNEL (escore)
Primary Tumor
0%	2 (6.7)	0 (0.0)
25-50%	3 (10.0)	0 (0.0)	0.885
51-75%	3 (10.0)	1 (14.3)
76-100%	22 (73.3)	6 (85.7)
Peritumoral area
0%	2 (7.7)	0 (0.0)
25-50%	1 (3.8)	0 (0.0)	1
51-75%	3 (11.5)	1 (20.0)
76-100%	20 (76.9)	4 (80.)
Lymph node metastasis
0%	2 (8.0)	0 (0.0)
25-50%	1 (4.0)	0 (0.0)	1
51-75%	5 (20.0)	1 (20.0)
76-100%	17 (68)	4 (80.0)

Pearson's chi-square test or Fisher's exact test, p<0,05