Table 1.

Comparison of Clinicopathological Parameters with the HIF-1α and LOXL-2 Immunoexpressions Using Kruskal-Wallis Test

Clinico-Pathological Parameter		No. of cases	HIF-1α expression		LOXL-2 expression
			Mean rank	p- value	Mean rank	p-value
Tumor stage (T)	Total	90		0.008*		0.968
	T1	21	62.6		45.5
	T2	33	41.29		46.68
	T3	8	38.62		43.31
	T4a	28	39.61		44.73
Nodal stage (N)	Total	90		0.821		0.988
	N0	31	43.18		46.19
	N1	42	45.13		43.99
	N2a	4	57.62		47.12
	N2b	10	50.45		48.2
	N2c	3	42		48.33
Clinical Stage	Total	90		0.095		0.979
	I	12	57.25		46.42
	II	13	32.15		48.04
	III	28	48.68		45.23
	IVa	37	43.97		44.51
Histological grade	Total	90		0.072		0.263
	I	38	50.17		47.39
	II	38	38.18		40.76
	III	14	52.68		53.21

*, indicates significant result