Table 6.

Results of variance analysis of drug loading efficiency (Y2).

Source	Sum of squares	df	Mean square	F-value	p-value
Model	323.52	9	35.95	29.20	<0.0001	Significant
A—CHOL : HSPC ratio	33.04	1	33.04	26.84	0.0004
B—drug–lipid ratio	220.36	1	220.36	179.00	<0.0001
C—drug incubation time	25.43	1	25.43	20.66	0.0011
AB	2.64	1	2.64	2.15	0.1737
AC	1.30	1	1.30	1.06	0.3281
BC	0.25	1	0.25	0.21	0.6596
A^2	0.75	1	0.75	0.61	0.4527
B^2	8.42	1	8.42	6.84	0.0258
C^2	35.07	1	35.07	28.49	0.0003
Residual	12.31	10	1.23
Lack of fit	5.61	5	1.12	0.84	0.5754	Not significant
Pure error	6.70	5	1.34
Cor total	335.83	19