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. 2021 May 27;11:601668. doi: 10.3389/fonc.2021.601668

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Copyright © 2021 Lei, Wang, Sun, Fu, Tian, Yang, Wang and Xia

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The expression of Nanog and CTCs in liver cancer peripheral blood and clinical liver cancer tissues. (A) Expression differences of E-cadherin, N-cadherin, and Nanog in 7 pairs of cancer and adjacent tissues (*P < 0.05 , 2-△△Ct). (B) The correlation between the phenotype of CTC and the Nanog positive rate in peripheral blood. (C–E) Correlation between phenotype and number of Nanog in peripheral blood. (F, G) Immunochemistry : Expression of E-cadherin, N-cadherin and Nanog in liver cancer tissues and their paired adjacent tissues (magnification, ×100 and ×400). ***P < 0.001.